Nabumetone is a medication to treat arthritis symptoms, such as swelling, pain, or stiffness, in the joints, especially those caused by osteoarthritis and rheumatoid arthritis. This medicine should only be used under a doctor's prescription.
Nabumetone is a non-steroidal anti-inflammatory drug that can relieve inflammation, fever, and pain.
This drug works by decreasing the production of prostaglandins, which generally increase when the body is injured or damaged. With decreased production of prostaglandins, complaints and symptoms can subside.
nabumetone trademark: Goflex
What is Nabumetone
| group | Non-steroidal anti-inflammatory drugs (NSAIDs) |
| Category | Prescription drugs |
| Benefit | Overcoming arthritis symptoms |
| Consumed by | Mature |
| Nabumetone for pregnant and lactating women | Category C:Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus. It is not known whether Nabumetone is absorbed in breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Film-coated tablets |
Precautions Before Taking Nabumetone
Nabumetone should not be used carelessly. The following are things you need to pay attention to before using nabumetone:
- Do not use nabumetone if you are allergic to this drug or to other classes of nonsteroidal anti-inflammatory drugs.
- Stop consuming alcohol and smoking while taking nabumetone because it can increase the risk of side effects.
- Tell your doctor if you have or have had asthma, heart disease, heart attack, nasal polyps, hypertension, liver disease, stroke, peptic ulcer, gastrointestinal bleeding, kidney disease, or a blood clotting disorder.
- Tell your doctor if you have recently had a heart bypass procedure.
- Do not operate machinery, drive, or perform activities that require alertness, after taking nabumetone.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- See your doctor right away if you have an allergic reaction or overdose after using nabumetone.
Dosage and Instructions for Use Nabumetone
Nabumetone is used to treat symptoms of arthritis (arthritis). The dose of nabumetone varies, this will be adjusted to the condition to be treated.
To relieve symptoms of osteoarthritis and rheumatoid arthritis in adults, the dose of nabumetone is 1,000 mg once a day as an initial dose. Continued dose 1,500–2,000 mg/day, divided into 1 or 2 daily doses. The maximum dose is 2,000 mg/day.
After the treatment is running, the doctor may adjust the dose according to the patient's condition and response to treatment.
How to Take Nabumetone Correctly
Always follow your doctor's instructions and read the instructions on the medicine package before taking nabumetone.
Swallow the nabumetone tablet whole with the help of a glass of water. Take nabumetone 1 or 2 times a day according to the doctor's instructions. It is recommended to take this drug after meals. Try not to lie down for at least 10 minutes after taking this medicine.
Do not increase or decrease the dose of nabumetone without consulting your doctor first.
Store nabumetone at room temperature, in a dry place, and away from sunlight. Keep out of reach of children. Make sure the nabumetone packaging is tightly closed before storing it.
Nabumetone Interactions with Other Drugs
The use of nabumetone together with other drugs can cause several interaction effects, including:
- Increased risk of gastrointestinal bleeding if used with corticosteroids, anticoagulants, SSRI antidepressants, antiplatelet or other nonsteroidal anti-inflammatory drugs
- Increases risk of hyperkalemia if used with drugs ACE inhibitor
- Decreases lithium or methotrexate discharge
- Increases renal effect when used with ciclosporin or tacrolimus
- Increases risk of damage to blood cells when used with zidovudine
Side Effects and Dangers of Nabumetone
The following are some of the side effects that can occur after taking nabumetone:
- Stomach ache
- Nausea or vomiting
- Diarrhea or constipation
- Bloating or passing wind
- Dizziness or headache
Check with your doctor if these side effects get worse or don't go away. See your doctor right away if you have an allergic drug reaction or any of the following serious side effects:
- Ears ringing
- Mental or mood changes
- Pain or difficulty swallowing
- Symptoms of bleeding in the digestive system, such as blood in the stool, coughing up blood, or vomiting resembling coffee grounds
- Heart problems, which can be characterized by swelling in the legs, unusual tiredness, weight gain
- Liver disorders, which can be characterized by jaundice, dark urine
