Proton Pump Inhibitors - Benefits, dosage and side effects

Proton pump inhibitor or proton pump inhibitors (PPIs) are a group of drugs used to prevent and treat acid reflux disease, peptic ulcers, duodenal ulcers, erosive esophagitis, Zollinger-Ellison syndrome, or bacterial infections. Helicobacter pylori.

Proton pump inhibitors work by blocking a special enzyme in the stomach wall, thereby reducing stomach acid production. When stomach acid production is reduced, complaints will subside.

In addition, this way of working will prevent the formation of wounds and help heal wounds in the stomach.

Precautions Before Using Proton Pump Blockers

Proton pump inhibitors should only be used with a doctor's prescription. Follow your doctor's recommendations and advice while on treatment with proton pump inhibitors. Before taking proton pump inhibitors, you should pay attention to the following points:

  • Tell your doctor about any allergies you have. Drug class proton pump inhibitor should not be used by patients who are allergic to any of the drugs included in this drug.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products.
  • Tell your doctor if you have or have had liver disease, kidney disease, hypomagnesemia, osteoporosis, fractures, dementia, stomach cancer, heart disease, diarrhea, or an autoimmune disease, such as lupus.
  • See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after using a proton pump inhibitor.

Side Effects and Hazards of Proton Pump Blockers

Side effects that can occur after using proton pump inhibitor drugs include:

  • Headache
  • Fever
  • Vomiting or nausea
  • Diarrhea or constipation
  • Stomach pain or bloating
  • Changes in the sense of taste or color of the tongue changes

Check with your doctor if the side effects above do not subside. Immediately see a doctor if you have an allergic reaction to the drug or a more serious side effect, such as:

  • Increased risk of fractures due to osteoporosis, kidney inflammation, or recurrence of lupus symptoms
  • Bacterial infection Clostridium difficile which can be characterized by complaints in the form of prolonged diarrhea, severe abdominal pain or cramps, the presence of blood or stool mucus
  • Low levels of magnesium in the blood which can be characterized by symptoms, such as slow, fast, irregular heartbeat, muscle stiffness, or seizures

In addition, long-term use of proton pump inhibitors can increase the risk of developing vitamin B12 deficiency.

Proton Pump Inhibitor Type, Trademark and Dosage

The following are the types of drugs that belong to the proton pump inhibitor class of drugs: 

1. Dexlansoprazole

Trademarks of dexlansoprazole:-

Condition: Erosive esophagitis

  • Mature: 60 mg, once daily, for 8 weeks. Maintenance dose 30 mg, once daily for 6 months.
  • Children 12 years old: 60 mg, once daily for 8 weeks. Maintenance dose 30 mg, once daily for 4 months.

Condition:Gastroesophageal reflux disease (GERD)

  • Mature: 30 mg, once daily for 4 weeks.

2. Esomeprazole

Trademarks: Arcolase, Depump, EMP, E-some, Esola, Esomax, Esozid, Esomax, Esomeprazole Sodium, Esoferr, Exocid, Ezol 20, Lanxium, Nexigas, Nexium Mups, Simprazole, S-Omevell

To find out the dosage and more information about this drug, please visit the esomeprazole drug page.

3. Lansoprazole

Trademarks: Campraz, Caprazol, Dobrizol, Erphalanz, Inazol, Inhipraz, Laz, Lanpracid, Lagas, Lanzogra, Ladenum, Lancid, Lansoprazole, Loprezol, Lapraz, Lexid, Prosogan FD, Prazotec, Sopralan 30, Zolesco

To find out the dosage and more information about this drug, please visit the lansoprazole drug page.

4. Omeprazole

Trademarks: Gastrofer, Inhipump, Meisec, Ofizol, Omeyus, Omeprazole, Omeprazole Sodium, Omberzol, OMZ, Esomax, Ozid I.V, Pumpitor, Protop, Redusec, Tamezole, Zolacap, Zollocid

To find out the dosage and more information about this drug, please visit the omeprazole drug page.

5. Pantoprazole

Trademarks: Ciprazole, Erprazole, Fastzol, Fiopraz, Ottozol, Pantomet, Pantomex, Pantopump 40, Pantorin, Pantozol 20, Pepzol, Pantera, Panso, Pranza, Panloc, Topazol, Pantoprazole Sodium, Panvell, Panzomed, Panto-Gas, Pepzol 20 , Pumpisel, Ulcan, Vomizole

To find out the dosage and more information about this drug, please visit the pantoprazole drug page.

6. Rabeprazole

Trademarks: Barole 10, Barole 20, Pariet

To find out the dosage and more information about this drug, please visit the rabeprazole drug page.