Selegiline is an adjunct medication used to control the symptoms of Parkinson's disease. This drug will be prescribed with Parkinson's drugs other, such as levodopa.
Selegiline works by increasing the amount of the hormone dopamine, which is a hormone that controls movement. Although it can be used as an adjunct therapy to control the symptoms of Parkinson's disease, it is not a cure for this condition.
Selegiline trademark: Jumex
What is Selegiline
| group | MAOIs |
| Category | Prescription drugs |
| Benefit | Controlling complaints in Parkinson's disease |
| Used by | Adults and seniors |
| Selegiline for pregnant and lactating women | Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus. It is not known whether selegiline can be absorbed in breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Shape | Tablet |
Warning Before Taking Selegiline
Selegiline should not be used carelessly. Follow the doctor's advice while undergoing treatment with this medicine. Before taking selegiline, you need to pay attention to the following things:
- Do not take selegiline if you have a history of allergies to this drug.
- Do not take selegiline if you are taking other antidepressant drugs, including fluoxetine.
- Do not eat foods that are high in tyramine, such as beef and soybeans, while on treatment with selegiline.
- Do not perform activities that require high alertness, such as driving a vehicle, after taking selegiline, as this medicine can make you dizzy.
- Tell your doctor if you are or have ever taken any medications, vitamin supplements, or herbal products.
- Tell your doctor if you have liver disease, hypertension, kidney disease, phenylketonuria.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- If you have an allergic drug reaction or overdose after taking selegiline, see a doctor immediately.
Dosage and Rules for Use of Selegiline
The dose of seregiline is determined based on the age and condition of the patient. The following are the dosages of selegiline based on their intended use:
- Treating Parkinson's disease in adults
Dosage: 5 mg, 2 times a day
Maximum dose: 10 mg
- Treating Parkinson's disease in the elderly
Dosage: 5 mg, 2 times a day
Maximum dose: 10 mg
Selegiline can also be used to treat depression. The type of selegiline preparation used to treat depression is: patches (koyo).
How to Take Selegiline Correctly
When taking selegiline, follow the doctor's advice and read the instructions on the medicine package. Selegiline can be taken in the morning and afternoon.
Make sure you always take selegiline at the same time every day to get maximum results.
If you forget to take your medicine, take it as soon as you remember if it is not too close to the next scheduled time to take your medicine. If it is near, ignore the missed dose and do not double the next dose.
Do not stop taking selegiline without consulting your doctor. While using this drug, do regular check-ups with your doctor so that your health condition can be monitored.
Store selegiline in a tightly closed container. Make sure the container is out of reach of children. Store well at room temperature and make sure it is not stored in a place that is too hot or in a humid place.
Selegiline Interactions with Other Drugs
Taking selegiline with other drugs can cause interaction effects such as:
- Increased risk of developing hypertension when used with amphetamines, rasagiline, bupropion, and clonazepam
- Increased risk of developing serotonin syndrome if used with antidepressant drugs, such as duloxetine, 5-hydroxytryptophan, escitalopram, and meperidine
- Increased risk of respiratory distress and hypotension when used with opioid drugs
- Increased side effects of levodopa
Selegiline can also increase the risk of dangerous increases in blood pressure when taken with foods or drinks that contain tyramine, such as sometimes soy, dried meat, or mushroom extract.
Side Effects and Dangers of Selegiline
There are some minor side effects that may occur after taking selegiline, including:
- Dizzy
- dry mouth
- Stomach ache
- Difficult to swallow
- Drowsiness
Check with your doctor if the above side effects occur for a long time and continuously. In addition to the side effects above, selegiline can cause more serious side effects and require examination by a doctor, such as:
- Severe headache
- Chest pain
- Heart beat
- Sweating
- Nausea and vomiting
- Stiff or sore neck
- Uncontrollable body movements
- hallucination
- Difficult to breathe
