Amyl nitrite is a vasodilator drug used to relieve angina or chest pain. In addition, this drug is also useful for dealing with cyanide poisoning.
Amyl nitrite works by relaxing blood vessel muscles. That way, the blood vessels will be wider and the supply of oxygen and blood to the heart will increase. This condition can reduce the workload of the heart.
In the treatment of cyanide poisoning, amyl nitrite will prevent the formation of cyanomethemoglobin which cannot deliver oxygen to cells or tissues. By preventing the formation of these compounds, normal metabolic processes can resume.
Amyl nitrite trademark: -
What is Amyl Nitrite
| group | Prescription drugs |
| Category | Vasodilators |
| Benefit | Treat angina and treat cyanide poisoning |
| Used by | Mature |
| Amyl Nitrite for pregnant and lactating women | Category C:Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus. It is not known whether amyl nitrite can be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Solution in ampoules by inhalation (inhalation) |
Warning Before Using Amyl Nitrite
Before using amyl nitrite, you need to pay attention to the following points:
- Tell your doctor about any allergies you have. Amyl nitrite should not be given to patients who are allergic to this drug.
- Tell your doctor if you have or are currently suffering from severe anemia, glaucoma, stroke, heart attack, hyperthyroidism, hypotension, or a recent head injury.
- Tell if you are or have recently undergone dialysis or hemodialysis.
- Avoid getting up too soon after lying down after using amyl nitrite, as this medicine can cause dizziness.
- Avoid consuming alcoholic beverages while using amyl nitrite, as it can cause dizziness, or a drop in blood pressure.
- Tell your doctor if you are taking any medications, supplements, or herbal products.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after using amyl nitrite.
Dosage and Rules for Use of Amyl Nitrite
Amyl nitrite should only be used according to a doctor's prescription. The following are general doses of amyl nitrite for adults based on their condition:
- Condition:The dosage is 0.3 ml (1 ampoule). Inhale through the nose 2-6 times. Repeat in 3-5 minutes if needed.
- Condition: Cyanide poisoning
The dose is 0.3 ml (1 ampoule), the contents are poured onto a cloth and placed in front of the patient's mouth, or the contents can be poured into an endotracheal tube, if the patient is being intubated. The drug is inhaled for 15–30 seconds.
How to Use Amyl Nitrite Correctly
Follow the doctor's advice and read the directions on the medicine package. Do not increase or decrease the dose without the doctor's permission, because it is feared that it can worsen the condition experienced.
When you start to feel an angina attack, it is advisable to sit down. Then crush the glass capsule or cloth-lined ampoule containing the amyl nitrite with your finger. Place the medicine near the nose while moving it back and forth. Inhale 1–6 times.
If you feel dizzy after using amyl nitrite, it is recommended to sit or lie down while the medicine is working.
Amyl nitrite is highly flammable. Therefore, keep the medicine away from heat and fire, especially when it is about to be used.
Store amyl nitrite at room temperature and avoid direct sunlight. Keep this medicine out of reach of children.
Amyl Nitrite Interaction with Other Drugs
Some of the interactions between drugs that can occur if amyl nitrile is used with other drugs are as follows:
- Increased risk of hypotension so severe that it can cause dizziness or fainting when used with sildenafil, avanafil, riociguat, or tadalafil
- Increased risk of methemoglobinemia when used with prilocaine or sodium nitrate
Amyl Nitrite Side Effects and Dangers
Some side effects that may occur after using amyl nitrite are:
- Dizziness, especially when getting up from a lying or sitting position
- Warmth in the face, neck, or chest (flush)
- Headache
- Fast pulse
- Nervous
- Nausea or vomiting
Consult a doctor if the above side effects do not subside immediately or get worse. You need to see a doctor immediately if you experience an allergic drug reaction or more serious side effects, such as:
- skin rash
- Unusual tired
- Blue lips, fingernails or palms
- Hard to breathe
- Fast or too slow heart rate
- Severe dizziness
- Faint
