Cyproheptadine - Benefits, dosage and side effects

Cyproheptadine is a medication to relieve allergy symptoms, such as sneezing, watery eyes, runny nose, hives, or itchy skin.

Cyproheptadine is a first-generation antihistamine drug that works by inhibiting the action of histamine substances. Histamine is a natural substance that will cause complaints and symptoms when a person is exposed to substances that trigger allergies (allergens). When the work of histamine is inhibited, the complaints and symptoms of allergies will subside.

Keep in mind that cyproheptadine cannot cure allergies, but only relieves the symptoms. The best way to prevent the appearance of allergy symptoms is to avoid the substance or ingredients,

Cyproheptadine trademarks:Bimatonin, Cydifar, Ennamax, Erphacyp, Esprocy, Graperide, Heptasan, Lycipron, Lexahist, Ponchohist, Profut, Pronam, Pronicy  

What is Cyproheptadine

groupPrescription drugs
BenefitRelieves allergy and eczema symptoms
Used byAdults and children aged 2 years and over
Cyproheptadine for pregnant and lactating womenCategory B: Animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women.

Cyproheptadine is not known to be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without telling your doctor.

Drug formTablets and caplets

Warnings Before Taking Cyproheptadine

Cyproheptadine must be used with a doctor's prescription. Some things to consider before taking cyproheptadine are:

  • Do not take cyproheptadine if you are allergic to this drug.
  • Tell your doctor if you have or have had glaucoma, peptic ulcer, urinary retention, asthma, emphysema, enlarged prostate gland or BPH, heart disease, hypertension, diabetes, hyperthyroidism, liver disease, seizures, kidney disease, or porphyria.
  • Do not drive a vehicle or do activities that require alertness after taking cyproheptadine, as this medicine may cause dizziness, drowsiness, or blurred vision.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking certain supplements, herbal products, or certain medications, such as MAOIs, such as isocarboxazid.
  • Tell your doctor that you are taking cyproheptadine if you are undergoing certain medical procedures, including laboratory tests and dental surgery.
  • See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after taking cyproheptadine.

Dosage and Instructions for Use of Cyproheptadine

The doctor will determine the dose of cyproheptadine according to the patient's age, condition, and body response. In general, the following is the dosage of cyproheptadine for the treatment of allergic reactions divided according to the age of the patient:

  • Mature: Initial dose 4 mg, 3-4 times daily. The maintenance dose is 4–20 mg per day. The maximum dose is 32 mg per day.
  • Children ages 2–6 years: 2 mg, 2-3 times daily. The maximum dose is 12 mg per day.
  • Children ages 7–14 years: 4 mg, 2-3 times daily. The maximum dose is 16 mg per day.

In addition, sometimes cyproheptadine can be used to prevent migraines, the dose is 4 mg, 2 times a day.

How to Take Cyproheptadine Correctly

Follow the doctor's advice and read the information listed on the medicine package before taking cyproheptadine. Do not increase or decrease the dose without consulting your doctor first.

Cyproheptadine can be taken before or after meals. Take cyproheptadine tablets or caplets with a glass of water. Swallow the medicine whole, do not chew or crush it.

Make sure that there is sufficient time between one dose and the next. Try to take cyproheptadine at the same time every day for maximum treatment.

If you forget to take cyproheptadine, take it immediately if the break with the next consumption schedule is not too close. If it is close, ignore it and do not double the dose.

During treatment with cyproheptadine, control according to the schedule given by the doctor, so that the condition and response to therapy can be monitored.

Store cyproheptadine at room temperature, and avoid direct sunlight. Keep this medicine out of reach of children.

Cyproheptadine Interactions with Other Drugs

There are several drug interactions that can occur if cyproheptadine is used with other medicines, including:

  • Increased effectiveness of cyproheptadine when used with class drugs monoamine oxidase inhibitors (MAOIs), such as isocarboxazide or selegiline
  • Increased risk of side effects such as drowsiness, blurred vision, dry mouth, excessive sweating, or stomach cramps when used with tricyclic antidepressants, such as amitriptyline or doxepin
  • Increased risk of developing severe respiratory distress when used with ketamine
  • Increased risk of occurrenceheat strokewhen used with zonisamide or topiramate
  • Increased risk of injury or irritation of the digestive tract when used with potassium supplements

Cyproheptadine Side Effects and Dangerse

Side effects that may arise after taking cyproheptadine include:

  • Drowsiness
  • Dry mouth, nose or throat
  • Dizziness or headache
  • Nauseous
  • Constipation
  • Blurred vision
  • Restless or overly excited, especially if used by children

Check with a doctor if the complaints mentioned above do not go away or get worse. See your doctor right away if you have an allergic reaction to a drug or experience more serious side effects, such as:

  • Excessive tiredness, confusion, or hallucinations
  • Tremors or shaking
  • Dizziness or ringing in the ears
  • Irregular or fast heartbeat
  • Difficult to urinate
  • Seizures