Gliquidone - Benefits, dosage and side effects

Gliquidone is a drug to lower blood sugar levels in patients with diabetestype 2 diabetes. The use of this drug must be accompanied by the application of a healthy lifestyle for effective treatment.

Gliquidone is a second-generation sulfonylurea antidiabetic drug that works by stimulating insulin production and increasing carbohydrate metabolism. That way, blood sugar levels can be more controlled.

This drug can only work if the beta cells of the pancreas are still producing insulin, so it cannot be used in the treatment of type 1 diabetes.

gliquidone trademark: Glurenorm, Gliquidone, Lodem

What is Gliquidone

groupPrescription drugs
CategorySulfonylureas antidiabetic
BenefitTreating type 2 diabetes
Consumed byMature
Gliquidone for pregnant and lactating womenCategory N:Not categorized.

It is not known whether Gliquidone is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug formTablet

Warnings Before Taking Gliquidone

Gliquidone should only be used with a doctor's prescription. There are several things you should pay attention to before taking gliquidone, including:

  • Do not take gliquidone if you are allergic to this drug. Tell your doctor about any allergies you have, including if you have ever been allergic to sulfa drugs.
  • Tell your doctor if you have or have had type 1 diabetes, liver disease, heart disease, G6PD deficiency, kidney disease, porphyria, or adrenal gland disease.
  • Do not consume alcoholic beverages while on treatment with gliquidone because it can increase the risk of developing hypoglycemia.
  • Tell your doctor that you are taking gliquidone before any surgery, including dental surgery.
  • Do not drive or do activities that require alertness after taking gliquidone, as this medicine can cause dizziness.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products.
  • See your doctor right away if you have an overdose or allergic reaction to the drug after taking gliquidone.

Dosage and Instructions for Use of Gliquidone

The doctor will prescribe gliquidone according to the patient's condition. The usual dose of gliquidone for adults with type 2 diabetes is 15 mg once daily.

The dose can be increased up to a maintenance dose of 45-60 mg per day which can be divided into 2-3 times of consumption. The maximum dose is 60 mg per drink or 180 mg per day.

How to Take Gliquidone Correctly

Always follow the doctor's advice and read the information on the drug packaging before taking gliquidone. Do not increase or decrease the dose of the drug without consulting your doctor first.

Gliquidone tablets are taken with meals. Swallow the gluquidone tablet whole with the help of a glass of water. Take gliquidone at the same time each day.

If you forget to take gliquidone, take it immediately if the interval between the next consumption schedule is not too close. If it is close, ignore it and do not double the dose. Tell your doctor if you frequently forget to take gliquidone.

Gliquidone cannot cure type 2 diabetes. In order for treatment to be more effective, patients must make changes to a healthier lifestyle, such as adjusting their diet, exercising regularly, and quitting smoking.

Check with the doctor and check blood sugar regularly so that the response to therapy can be monitored.

Store gliquidone in a dry place, at room temperature, and away from sunlight. Keep out of reach of children.

Gliquidone Interactions with Other Drugs

The use of gliquidone together with other drugs can cause several interaction effects, including:

  • Increased blood sugar lowering effect when used with ACE inhibitors, allopurinol, azole antifungals, cimetidine, clofibrate, anticoagulants, halofenates, octreotide, ranitidine, sulfinpyrazone, tricyclic antidepressants, MAOIs, chloramphenicol, or tetracyclines
  • Increased risk of developing hypoglycemia and masking symptoms of hypoglycaemia when used with beta-blocking drugs
  • Decreased blood sugar lowering effect when used with adrenaline, aminoglutethimide, diazoxide, rifamycin, chlorpromazine, corticosteroids, birth control pills, hormone medications, or thiazide diuretics

Side Effects and Dangers of Gliquidone

One of the side effects that can occur due to the use of gliquidone is hypoglycemia. Some of the symptoms of hypoglycemia are difficulty concentrating, shaking, pale, cold sweats, or palpitations.

Immediately consume sweet foods or drinks if you feel these complaints. If the complaints get worse, go to the doctor immediately.

In addition, some other side effects that can occur after taking gliquidone:

  • Nauseous
  • Throw up
  • Stomach ache
  • Diarrhea
  • Dizzy
  • Weight gain

Check with your doctor if these side effects don't go away or get worse. See a doctor immediately if you have an allergic reaction to the drug which can be characterized by swelling of the lips or eyelids, a rash on the skin, or difficulty breathing.