Etanercept is a cure for treat plaque psoriasis juvenile idiopathic arthritis. This drug can also be used to prevent more severe joint damage due to rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis. Etanercept is sometimes combined with methotrexate.
Etanercept works by inhibiting the work of tumor necrosis factor alpha (TNF-α). TNF- is responsible for the appearance of inflammatory symptoms in psoriasis, rheumatoid arthritis, or juvenile idiopathic arthritis. By inhibiting the work of TNF-α, the symptoms of inflammation can also be reduced.
This drug is available in the form of an injection that can only be given by a doctor or medical officer under the supervision of a doctor. Keep in mind that these drugs only relieve symptoms and cannot cure these diseases.
Trademark etanercept: Enbrel, Etarfion
What's that Etanercept
| group | Prescription drugs |
| Category | Immunosuppressants |
| Benefit | treat psoriasis, juvenile idiopathic arthritis, and relieve symptoms rheumatoid arthritis and ankylosing spondylitis |
| Used by | Adults and children |
| Etanercept for pregnant and lactating women | Category B: Animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women. Etanercept can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Inject |
Warning Before Using Etanercept
There are several things you should pay attention to before using etanercept, including:
- Tell your doctor about any allergies you have. Etarnecept should not be given to patients who are allergic to this drug.
- Tell your doctor if you have diabetes, seizures, cancer, heart failure, blood disorders, multiple sclerosis, Guillain Barre syndrome, or an infectious disease, such as hepatitis B, HIV/AIDS, tuberculosis.
- Tell your doctor if you have any symptoms of infection, such as fever, chills, cough, coughing up blood, or diarrhea.
- Talk to your doctor if you plan to vaccinate with a live vaccine, such as the BCG vaccine, while on treatment with etarcept.
- As much as possible, avoid close contact with people with infectious diseases that are easily transmitted, such as the flu or measles, during treatment with etanercept, because it can increase your risk of contracting it.
- Tell your doctor if you are taking any other medicines, including other immunosuppressant drugs, herbal products, or supplements.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after using etanercept.
Dosis and Rules of Use Etanercept
Etanercept will be given by a doctor or medical officer under the supervision of a doctor by injection into the skin layer (subcutaneously / SC) in the thigh, stomach, or arm area. The dose of etanercept given depends on the condition to be treated and the age of the patient. Here is the explanation:
Condition: ankylosing spondylitis, rrheumatoid arthritis
- Mature: 25 mg, 2 times a week, or 50 mg, once a week.
Condition: psoriasis
- Mature: 25 mg, 2 times a week, or 50 mg, once a week.
- Children 12 years old: 0.4 mg/kg, 2 times a week, or 0.8 mg/kg, once a week.
Condition: Juvenile idiopathic arthritis
- Children 2 years old: 0.4 mg/kg, 2 times a week, or 0.8 mg/kg, once a week.
How to use Etanercept correctly
Etancercept injection will be given directly by a doctor or medical officer under the supervision of a doctor by injection under the layer of skin in the thigh, stomach, or arm area.
During treatment with etarnecept, you will need to undergo regular complete blood counts and monitoring for side effects.
Follow your doctor's advice and advice while you are on treatment with etanercept. Do not stop treatment without consulting your doctor first.
Interaction Etanercept with other drugs
The following are some of the effects of interactions that may occur when etanercept is used with other medicines:
- Decreased white blood cell count when used with sulfasalazine
- Increased risk of serious infection if used with mycophenolate mofetil, abatacept, methotrexate, adalimumab, anakinra, cyclophosphamide, or corticosteroid drugs, such as cortisone
- Decreased levels and effectiveness of atorvastatin or oxycodone
- Decreased effectiveness of live vaccines, such as the BCG vaccine
Side Effects and Dangers Etanercept
Side effects that can arise after using etanercept include:
- Pain, itching, redness, or swelling, at the injection site
- Headache
- Stomach pain, nausea, vomiting, or heartburn
- Cold symptoms appear, such as nasal congestion or sneezing
Report to your doctor if you have an allergic drug reaction or experience more serious side effects, such as:
- Tingling, numbness, or weakness in the hands or feet
- Visual disturbance
- Easy bruising or paleness
- Red rash on nose or cheeks
- Severe headache or seizures
- Jaundice or severe abdominal pain
- Difficulty breathing accompanied by swelling in the legs
In addition, the use of etanercept can increase the risk of fatal infectious diseases. Go to the doctor immediately if you experience symptoms of infection, such as fever, chills, persistent cough, abnormal vaginal discharge, or thrush in the mouth.
