Oxacillin is a drug to treat bacterial infections Staphylococcus resistant to the antibiotic penicillin G. Infection Staphylococcus can cause variety diseases, such as pneumonia (pneumonia), heart infections (endocarditis), or bone and muscle infections (osteomyelitis).
Oxacillin belongs to the type of penicillin antibiotic. This drug works by inhibiting the formation of bacterial cell walls. That way the growth of bacteria that cause infection can be stopped. This drug is available in the form of an injection that can only be given by a doctor or medical officer under the supervision of a doctor.
Oxacillin trademark: -
What is Oxacillin
| group | Prescription drugs |
| Category | Penicillin antibiotics |
| Benefit | Overcoming bacterial infection Stapylococcus |
| Used by | Adults and children |
| Oxacillin for pregnant and lactating women | Category B: Animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women. Oxacillin can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Inject |
Precautions Before Using Oxacillin
There are several things you should pay attention to before using oxacillin, including:
- Tell your doctor about any allergies you have. Oxacillin should not be given to patients who are allergic to this drug or to penicillin antibiotics.
- Tell your doctor if you have or have had asthma, kidney disease, heart failure, or liver disease.
- Tell your doctor if you are on a low-salt diet, as some oxacillin products have sodium salt in them.
- Tell your doctor if you plan to vaccinate with a live vaccine, such as the typhoid vaccine, because oxacillin can reduce the effectiveness of the vaccine.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after taking oxacillin.
Oxacillin Dosage and Usage
Oxacillin injection will be given directly by a doctor or medical officer under the supervision of a doctor. The dose will be adjusted according to the patient's health condition and age.
In general, the following is the dosage of oxacillin to treat S . infectiontapylococcus resistant to penicillin G:
- Mature: 250–500 mg, every 4–6 hours, by injection into a muscle (intramuscularly/IM) or into a vein (intravenous/IV). The dose may be increased to 1,000 mg for severe infections.
- Children: 50–100 mg/kgBW per day, by injection into a vein (intravenous/IV).
How to Use Oxacillin Correctly
Oxacillin injection will be given in a hospital or health facility by a doctor or medical officer under the supervision of a doctor.
Follow your doctor's advice and recommendations while you are on treatment with oxacillin. Do not stop taking medication without consulting your doctor first.
During treatment, you will undergo regular complete blood counts to monitor your condition, response to therapy, and possible side effects.
Oxacillin Interactions with Other Drugs
The following are some of the effects of interactions that may occur if oxacillin is used with other medicines:
- Increased levels of methotrexate in the blood which can cause side effects, such as nausea, vomiting, sores in the mouth, or low blood cell counts
- Increased blood levels of oxacillin when used with probenecid
- Decreased effectiveness of live vaccines, such as BCG vaccine or typhoid vaccine
- Decreased effectiveness of oxacillin when used with tetracycline or doxycycline
Oxacillin Side Effects and Dangers
Tell your doctor or medical officer if the following side effects do not subside or get worse:
- The injection site looks red, itchy, or swollen
- Diarrhea
- Nausea and vomiting
In addition, report to your doctor immediately if you experience an allergic reaction to the drug or experience more serious side effects, such as:
- Easy bruising or paleness
- Bloody urine or difficulty urinating
- Unusual mood swings or fatigue
- Loss of balance and coordination
- Jaundice or severe abdominal pain
- Seizures
- Diarrhea that doesn't stop, bloody stools, or mucus
