Paromomycin is a drug for menwish parasitic infections, such as amebiasis in the digestive tract. This medicine too can be used as adjunct therapy in handling hepatic encephalopathyk.
Paromomycin works by stopping the growth of parasites in the intestines, so the infection can be resolved. While as an additional drug for hepatic encephalopathy k , paramomycin will help stop the growth of bacteria that produce ammonia.
Paromomycin trademark: Gabryl
What is Paromomycin
| group | Prescription drugs |
| Category | Aminoglycoside antibiotics |
| Benefit | Treating amebiasis in the gastrointestinal tract or as an adjunct in the treatment of hepatic encephalopathy. |
| Consumed by | Adults and children |
| Paromomycin for pregnant and lactating women | Category C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus. It is not known whether Paromomycin is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Tablets and syrup |
Precautions Before Taking Paromomycin
Paromomycin should only be used as prescribed by a doctor. The following are some things you need to pay attention to before taking paromomycin:
- Tell your doctor about any allergies you have. Paramomycin should not be given to patients who are allergic to this drug or to other aminoglycoside antibiotics, such as gentamicin.
- Tell your doctor if you have or have had kidney disease or a digestive disorder, such as intestinal obstruction or ulcerative colitis.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- Consult your doctor if you plan to vaccinate with live vaccines while on treatment with paromomycin.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- See your doctor right away if you have an allergic reaction, serious side effects, or overdose after taking paromomycin.
Dosage and Instructions for Use of Paromomycin
The dose of paromomycin varies in each patient. The doctor will determine the dose according to the patient's condition and body response. The following is the dosage of paromomycin for children and adults divided according to the condition to be treated:
- Condition: Amebiasis in the digestive tract
The dose is 20–25 mg/kg, 3 times a day for 5–10 days.
- Condition: Adjunct therapy for hepatic encephalopathy k
The dose is 4,000 mg in divided doses for 5–6 days.
- Condition: Infection Dientamoeba fragilis The dose is 25–30 mg/kg, 3 times a day for 7 days.
- Condition: Worm infections, such as T. saginata or T. solium
The dose is 11 mg/kgBW, divided into 4 doses.
How to Take Paromomycin Correctly
Take paromomycin according to the doctor's advice and the instructions on the medicine package. Do not change the dose without consulting your doctor first.
Paromomycin should be taken after meals. Do not stop treatment with paromomycin even if you feel better, unless advised by your doctor.
If you forget to take paromomycin, take it immediately if it is not close to the time for your next dose. If it is near, ignore the missed dose. Do not double the dose of paromomycin to make up for a missed dose.
Store paromomycin at room temperature and place in a closed container. Keep the medicine away from direct sunlight and out of reach of children.
Interaction of Paromomycin with Other Drugs
The following are some of the effects of interactions that may occur if Paromomycin is taken with other medicines:
- Decreased effectiveness of live vaccines, such as BCG vaccine or typhoid vaccine
- Increased effect of tubocurarine, atracurium, or doxacurium, so that it can increase the risk of respiratory disorders
Paromomycin Side Effects and Dangers
Some of the side effects that can occur after taking paromomycin are:
- Diarrhea
- Nausea or vomiting
- Stomach pain or stomach cramps
- Loss of appetite
- Hot and burning feeling in the chest (hearthburn)
Check with a doctor if the complaints mentioned above do not go away or get worse. See your doctor right away if you have an allergic reaction to a drug or experience more serious side effects, such as:
- Sudden ringing in the ears or deafness
- Severe dizziness or headache
- Oily stool
- Seizures
- Numbness or tingling
- Unusual muscle aches, fatigue, and weakness
In addition, the use of paromomycin in the long term can increase the risk of fungal infections, such as candidiasis.
