Eptifibatide - Benefits, dosage and side effects

Eptifibatide is a drug used to prevent complications in the form of blood clots in patients with coronary heart disease. Eptifibatide can also be used before, During, and after, angioplasty process. This medicine can only be used with a doctor's prescription.

Eptifibatide is an antiplatelet drug that works by blocking platelets (platelets) from sticking together and forming blood clots. This drug is given by intravenous injection and infusion.

eptifibatide trademark: -

What's that Eptifibatide?

CategoryPrescription drugs
BenefitPrevent complications of coronary heart disease and angioplasty surgery
Used byMature
Eptifibatide for pregnant and lactating womenCategory B: Animal studies have not shown a risk to the fetus, but there are no controlled studies in pregnant women. Eptifibatide is not known to be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Precautions Before Using Eptifibatide:

  • Do not use eptifibatide if you are allergic to this drug. Before treatment with eptifibatide, you need to tell your doctor about any allergies you have.
  • Tell your doctor about your past or current medication history, especially if you are taking other NSAIDs, anticoagulants, antiplatelet or thrombolytics.
  • Tell your doctor if you have a history of severe kidney disease, severe liver disease, hemophilia, thrombocytopenia, uncontrolled hypertension, stroke, brain tumor, arteriovenous malformation, other internal bleeding, vasculitis, have had a serious injury, or have had surgery within 6 months. the last week. Eptifibatide is not recommended for patients with these conditions.
  • Do not consume alcohol while on treatment with eptifibatide.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • You will need to have regular blood tests while taking eptifibatide so that your doctor can monitor your condition and your response to this drug.
  • Tell your doctor right away if you have an allergic reaction or overdose after using eptifibatide.

Doseand Rules of UseEptifibatide

The dose of eptifibatide given by your doctor depends on the condition you want to treat. The following is an explanation of common eptifibatide dosages:

Condition: unstable angina or coronary heart disease

  • Initial dose: 180 mcg/kgBW given by injection through a vein (IV/intravenous).
  • Follow-up dose: 2 mcg/kg/minute by infusion up to a maximum of 72 hours.
  • If the patient undergoes percutaneous coronary intervention (PCI), the infusion of eptifibatide was continued 18–24 hours after the procedure.

Condition: angioplasty in cardiovascular disorders

  • First dose: 180 mcg/kgBW by IV injection before starting the angioplasty procedure. Followed by a dose of 2 mcg/kgBW/minute via infusion.
  • Second dose: 180 mcg/kg by IV injection given 10 minutes after the first dose. The dose will be continued by infusion until the patient is discharged from the hospital or for up to 18–24 hours (minimum duration of infusion is 12 hours).

How to Use Eptifibatide Correctly

Eptifibatide should only be given by a doctor or medical personnel under the supervision of a doctor. This drug is used by injection through a vein. The dose and duration of use of eptifibatide will be adjusted to the patient's condition. Schedule for injection or infusion will be given by the doctor.

Avoid activities that increase your risk of bleeding or injury if you are new to eptifibatide. Brush your teeth gently and shave your beard or mustache carefully, to prevent bleeding.

Eptifibatide should be stored in a refrigerator at 2–8°C. This medicine should not be exposed to direct sunlight. Keep eptifibatide out of the reach of children.

Eptifibatide Interactions with Other Drugs

Eptifibatide can cause drug interactions when used in combination with other drugs. Drug interactions that can occur are an increased risk of bleeding if eptifibatide is used with anticoagulant drugs, such as heparin, antiplatelet agents, such as clopidogrel and ticagrelor, or thrombolytic drugs, such as alteplase.

Eptifibatide Side Effects and Dangers

Some of the side effects that can occur after using eptifibatide are:

  • Dizzy
  • The appearance of bleeding, including bruising, hematuria, bloody stools, or vomiting blood
  • Irregular heartbeat (arrhythmia)
  • Low blood pressure (hypotension)
  • Back pain
  • Pain in the injected or injected area

Call your doctor right away if you have any of the above symptoms or if you have an allergic reaction to the drug, which is characterized by swelling of the lips and eyelids, difficulty breathing, an itchy skin rash.