Ceftizoxime is an antibiotic drug used to treat various diseases caused by bacterial infections, such as gonorrhea and urinary tract infections. This medicine can only be used with a doctor's prescription.
Ceftizoxime is a third-generation cephalosporin antibiotic that is available in injectable form. Ceftizoxime works by binding to and blocking enzymes peptidoglycan which is used to form the cell wall of bacteria.
Ceftizoxime trademark: Cefim, Cefizox, Ceftizoxime Sodium, and Tizos
What's that Ceftizoxime?
| group | Cephalosporin antibiotics |
| Category | Prescription drugs |
| Benefit | Treating bacterial infections |
| Used by | Adults and children |
| Ceftizoxime for pregnant and lactating women | Category B: Studies in animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women. Ceftizoxime can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Shape | Inject |
Precautions Before Using Ceftizoxime:
- Do not use ceftizoxime if you have a history of allergies to this drug.
- Tell your doctor if you have a history of allergy to penicillins or other cephalosporins.
- Tell your doctor if you are taking certain medications, supplements, or herbal remedies.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you have a history of kidney disease, bronchial asthma, or digestive disorders, such as colitis.
- Do not vaccinate with live vaccines, such as typhoid vaccine, while you are taking ceftizoxime.
- See a doctor immediately if you have an allergic reaction to the drug or an overdose after using ceftizoxime.
Doseand Rules of UseCeftizoxime
The dose of ceftizoxime that your doctor prescribes depends on your age, condition, and the patient's response to the drug. The following is the general dose of ceftizoxime based on the patient's condition:
Condition: Gonorrhea
- Mature
1 g single dose intramuscular (IM) injection.
Condition: Urinary tract infection
- Mature0.5 g per 12 hours given by IM injection or intravenous (IV) injection.
Condition: Other bacterial infections, such as bronchitis, cholangitis, cystitis, bacterial endocarditis, cholecystitis, pneumonia, prostatitis, peritonitis, or septicemia.
- Mature
0.5–2 g per day, divided into 2–4 separate doses by IM or IV injection. For severe infections, the dose may be increased to 4 g per day.
- Children6 monthsDose: 40–80 mg/kg per day, divided into 2–4 separate doses. For severe infections, the dose may be increased to 120 mg/kg per day.
How to Use Ceftizoxime Correctly
Ceftizoxime injection should only be given by a doctor or medical personnel under the supervision of a doctor. This drug is used by injection into a muscle or vein.
The duration of the use of ceftizoxime will be adjusted to the patient's condition. The doctor will give you a schedule for the injection of this drug. Follow the rules and schedule given by the doctor. Do not stop treatment carelessly because it can increase the risk of re-infection.
Ceftizoxime should be stored in a refrigerator at -20°C. Keep medicine out of reach of children.
Ceftizoxime Interactions with Other Drugs
Ceftizoxime can cause drug interactions when used together with other drugs. Drug interactions that can occur are an increased risk of side effects when used with probenecid.
In addition, the use of ceftizoxime together with vaccination with live vaccines can also reduce the effectiveness of the vaccine.
Ceftizoxime Side Effects and Dangers
Ceftizoxime rarely causes side effects. This drug is more likely to cause side effects when used by people with kidney or liver problems. Some of the side effects that can occur after using ceftizoxime are:
- Nauseous
- Throw up
- Diarrhea
- Pain and swelling at the injection site
- Fever
- Liver disfunction
- Headache
Although rare, the use of ceftizoxime can also increase the risk of disorders of the digestive tract, such as: pseudomembranous colitis, kidney damage, anemia, thrombocytopenia, leukopenia, thrush, or inflammation of the vagina.
See your doctor right away if you experience any of the side effects listed above or have an allergic reaction to the drug which can be characterized by itching, skin rash, difficulty breathing, or swelling of the lips and eyelids.
