Cefpirome - Benefits, dosage and side effects

Cefpirome is an antibiotic that is useful for treating diseases caused by bacterial infections, such as lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, and septicemia.

Cefpirome is a cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis. Cefpirome is available in 1 gram injection powder vials.

Cefpirome trademark: Bactirom, Cefmer, Cefpirome, Cefpirome Sulfate, Erpharom, Interome, and Lanpirome.

What's that Cefpirome?

groupCephalosporin class of antibiotics
CategoryPrescription drugs
BenefitTreating upper and lower urinary tract infections, skin and soft tissue infections, lower respiratory tract infections, infections in neutropenic patients, and bacteremia or septicemia.
Used byMature
Cefpirome for pregnant and lactating womenCategory B: Studies in animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women.

Cefpirome may be absorbed into breast milk. If you are breastfeeding, consult your doctor first before using this medicine.

Drug formInjection powder.

Precautions Before Using Cefpirome

  • Do not use this drug if you have a history of allergy to cefpirome, other cephalosporin antibiotics, and penicillin antibiotics.
  • Tell your doctor if you have a history of kidney or blood disorders.
  • Tell your doctor if you are taking any medications, supplements, and herbs before using this medication.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Be careful if you use it for children less than 12 years old.
  • Call your doctor right away if you have an allergic reaction or overdose.

Dosage and Instructions for Use Cefpirome

The dose of cefpirome will be given by the doctor depending on the patient's condition. The following is the dose of cefpirome for adults divided according to their condition:

  • Upper and lower urinary tract infections (UTIs)

    1 g is given by intravenous injection every 12 hours. The dose may be increased up to 2 g depending on the severity.

  • Skin and soft tissue infections

    1 g is given by intravenous injection every 12 hours. The dose may be increased up to 2 g depending on the severity.

  • Lower respiratory tract infection

    1-2 g given by intravenous injection every 12 hours

  • Infection in patients with neutropenia, bacteremia, or septicemia

    2 g is given by intravenous injection every 12 hours.

How to use Cefpirome correctly

Cefpirome injection can only be given by a doctor or medical personnel under the supervision of a doctor.

This medicine needs to be stored at room temperature, away from humid air, heat, and direct sunlight. Keep this medicine out of reach of children.

Cefpirome should not be used when it is cloudy or other particles are found in it.

Interaction Cefpirome with other drugs

If used with certain drugs, cefpirome can cause interactions such as:

  • Increased blood levels of cefpirome, when used with probenecid.
  • Increased risk of kidney damage, if used with aminoglycoside antibiotics or diuretic drugs.

Side Effects and Dangers Cefpirome

Side effects that can arise from the use of cefpirome include:

  • Swelling or irritation at the injection site
  • Nauseous vomit
  • Diarrhea
  • Fever
  • Eosinophilia
  • Candidiasis

Although rare, some of the more serious side effects listed below can also occur after using cefpirome:

  • Hemolytic anemia
  • Agranulocytosis
  • Thrombocytopenia
  • encephalopathy
  • Acute kidney failure
  • Liver disfunction
  • Seizures

Immediately see a doctor if you experience these symptoms or experience an allergic drug reaction, such as redness of the skin, swelling of the mouth and face, and shortness of breath.