Prochlorperazine - Benefits, dosage and side effects

Prochlorperazine is a drug used to treat symptoms of schizophrenia and anxiety disorders. Prochlorperazine is also used to treat nausea and vomiting which heavy.

Prochlorperazine is an antipsychotic drug. This drug can also be used to reduce nausea and vomiting. This drug works by blocking the function of dopamine in the brain. Prochlorperazine is not used to treat behavioral disorders and psychotic symptoms in people with dementia.

What's thatProchlorperazine?

groupAntipsychotic
CategoryPrescription drugs
BenefitRelieves the symptoms of schizophrenia
Consumed byAdults and children over 2 years old
Prochlorperazine for pregnant and lactating womenCategory C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus

Prochlorperazine may be absorbed into breast milk. Therefore, it should not be used during breastfeeding.

Drug formOral tablets (which are taken by mouth), suppositories (through the rectum), and injections

Warnings Before Using Prochlorperazine:

  • Do not use prochlorperazine if you are allergic to this drug or to other phenothiazines, such as trifluroperazine, chlorpromazine, and fluphenazine.
  • Do not use prochlorperazine if you are pregnant or breastfeeding.
  • Do not consume alcoholic beverages while on treatment with prochlorperazine.
  • Prochlorperazine should not be used in people with dementia, children under 2 years of age, or children who weigh less than 10 kg.
  • Prochlorperazine may cause temporary dizziness, drowsiness, and blurred vision. Therefore, do not drive or do activities that require alertness after taking this medicine.
  • Prochlorperazine can make you more sensitive to sunlight. Therefore, avoid exposure to the scorching sun, or apply sunscreen and wear closed clothes when you are outdoors during the day.
  • Prochlorperazine can make you sweat less or less, increasing your risk of developing heat stroke. Therefore, avoid taking a steam bath or exercising in hot weather while using this medicine.
  • Tell your doctor if you have or have had glaucoma, asthma, Reye's syndrome, seizures, intestinal obstruction, heart disease, COPD, difficulty urinating or blood and immune system disorders.
  • Tell your doctor if you have an adrenal gland tumor, kidney disease, liver disease, low blood pressure, brain tumor, breast cancer, or have had chemotherapy.
  • Tell your doctor before having surgery if you are taking prochlorperazine.
  • Call your doctor right away if you experience an allergic reaction or overdose after taking this medicine.

Dosage and Instructions for Use of Prochlorperazine

The distribution of prochlorperazine dosage will be adjusted according to the form of drug, condition, and age of the patient. The following are the dosages of prochlorperazine for adults, grouped by form of the drug:

Drug form: Intramuscular/IM (through a muscle) and intravenous/IV (through a vein) injection

  • Condition: relieve nausea and vomiting

    12.5 mg IM. Dosage may be repeated every 3–4 hours or 2.5–10 mg slowly IV. The maximum dose is 40 mg daily.

  • Condition: relieves symptoms of schizophrenia

    10–25 mg, 2–3 times daily.

Drug form: tablet

  • Condition: nausea and vomiting

    Preventive dose: 5–10 mg, 2–3 times daily. Treatment dose: 20 mg, followed by 10 mg at 2 hours thereafter.

  • Condition: vertigo due to Meniere's disease or labyrinthitis

    5 mg, 3 times a day. The dose may be increased to 30 mg daily. The dose will be gradually reduced to 5–10 mg daily after a few weeks

  • Condition: relieves symptoms of severe anxiety disorder (as adjunctive therapy)

    15-20 mg daily, divided doses. The maximum dose is 40 mg daily.

  • Condition: relieves symptoms of schizophrenia

    12.5 mg, 2 times daily for 7 days. The dose may be increased every 4–7 days.

Drug form: suppositories (through the rectum)

  • Condition: relieve nausea and vomiting

    25 mg, 2 times a day.

Talk to your doctor about the dosage of prochlorperazine for children and the elderly. Especially for children, the dose of prochlorperazine will be adjusted according to the child's weight.

How to Use Prochlorperazine Correctly

Prochlorperazine is used only with a doctor's prescription. Be sure to read the instructions on the medicine package before starting to use prochlorperazine. If in doubt, consult a doctor.

Take prochlorperazine tablets before or after meals. Try to take it at the same time so you don't miss a dose or forget it.

If you forget to take prochlorperazine tablets, do it as soon as you remember if the break with the next consumption schedule is not too close. If it is close, ignore it and do not double the dose.

Do not use prochlorperazine injectable form carelessly. Injectable prochlorperazine should only be given by a doctor or medical personnel under the supervision of a doctor.

Insert the prochlorperazine suppository into the rectum in a lying position. After the medication is in, stay lying down for a few minutes. Try not to have a bowel movement for at least 1 hour after using this medicine.

If you are using prochlorperazine in the long term, check your health condition with your doctor regularly and consult with your doctor first before stopping treatment.

Store prochlorperazine in a room at room temperature. Keep away from direct sunlight and humid air. Keep this medicine out of reach of children.

Interactions of Prochlorperazine with Other Drugs

Prochlorperazine may cause interaction effects when used with the following medicines:

  • Sedatives and barbiturates. The effect is to increase the risk of central nervous system depression.
  • Metoclopramide. The effect is to increase the risk of side effects of prochlorperazine.
  • The effect is to decrease the effectiveness of prochlorperazine.
  • The effect is to increase the risk of heart rhythm disturbances.
  • Lithium. The effect is to increase the risk of nerve poisoning.
  • Carbamazepine. The effect is to increase the risk of occurrence
  • Its effect is to decrease the absorption of prochlorperazine.
  • Hypoglycemic drugs. The effect is a decrease in the effectiveness of hypoglycemic drugs.
  • Anticoagulants taken by mouth (oral). The effect is a decrease in effectiveness

Side Effects and Dangers of Prochlorperazine

Some of the side effects that usually appear after using prochlorperazine are:

  • Hypotension
  • Insomnia
  • Nausea and vomiting
  • Dizzy and dizzy
  • Difficulty urinating (urinary retention)
  • Low sodium levels (hyponatremia)
  • High blood sugar levels (hyperglycemia)
  • Yellowing of the skin and whites of the eyes (jaundice)
  • Intestinal obstruction (obstruction)
  • Blood disorders
  • Tardive dyskinesia
  • Heart rhythm disturbances
  • cardiac arrest

Immediately see a doctor if you experience the above complaints and symptoms after using prochlorperazine, or have an allergic reaction to the drug, such as an itchy skin rash, swelling of the lips and eyelids, and difficulty breathing.