Fluphenazine - Benefits, dosage and side effects

Fluphenazine is an antipsychotic drug that is useful for treating mental disorders, such aselike schizophrenia. Fluphenazine works by balancing neurotransmitters, which are chemicals that carry signals or messages in the brain.

Fluphenazine will reduce the frequency and episodes of hallucinations, delusions, and abnormal behavior in people with schizophrenia. The use of fluphenazine can help people with schizophrenia or mental disorders to perform daily activities.

Fluphenazine should be used under a doctor's prescription. Fluphenazine is available in the form of an injection that will be given by a doctor.

Fluphenazine trademark: Siczonoate.

What is Fluphenazine?

CategoryPrescription drugs
BenefitOvercoming the symptoms of schizophrenia and psychotic disorders.
Consumed byMature
Fluphenazine for pregnant and lactating womenCategory C: Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women. Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not known whether fluphenazine is absorbed into breast milk. Consult your doctor if you want to use this medicine during breastfeeding.

Drug formInject

Warnings Before Using Fluphenazine:

  • Do not use fluphenazine in patients with a history of allergy to fluphenazine or to other phenothiazines, such as chlorpromazine, prochlorperazine and perphenazine.
  • Do not use fluphenazine in people with dementia, paeochromocytoma, and in coma or major depression.
  • Tell your doctor if you have glaucoma, enlarged prostate, hyperthyroidism, and heart, liver, and kidney disorders.
  • Tell your doctor if you have a history of seizures and disorders of the nervous system, such as brain tumors and infections of the brain.
  • Tell your doctor if you are taking any other medications, supplements, or herbal remedies before taking fluphenazine.
  • Tell your doctor if you are going to have any surgical procedures, including dental surgery, before using this medicine.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy, before using fluphenazine.
  • If an allergic drug reaction or overdose occurs after using fluphenazine, see a doctor immediately.

Dosage and Rules for Use of Fluphenazine

The dose of fluphenazine will be adjusted by the doctor according to the patient's condition. Injections are only given by a doctor or medical personnel under the supervision of a doctor. In general, the starting dose of fluphenazine is 12.5 mg. The next dose is 12.5-100 mg with a time span between doses of 2-6 weeks or as needed.

How to Use Fluphenazine Correctly

Follow the doctor's instructions during fluphenazine treatment so that the treatment effect can be optimal.

Patients taking fluphenazine should have regular check-ups with the doctor, both for drug administration and to monitor their condition in general.

During treatment with fluphenazine, patients will be asked to undergo blood tests. Blood test results can be used as a reference for doctors to consider the next dose of fluphenazine.

Fluphenazine can cause dizziness and fainting when getting up too quickly from a lying position. When using fluphenazine, exercise caution, especially when you wake up.

Follow the schedule that has been made by the doctor so that the treatment is effective. Do not stop regular visits without the doctor's permission, even if the symptoms are getting better. If you miss a regular visit, tell your doctor right away.

Fluphenazine Interactions with Other Drugs

When used together with certain drugs, fluphenazine can cause interaction effects such as:

  • Increased risk of fatal side effects, such as central nervous system depression, when used with barbiturates, opioids, and antihistamines.
  • Reduced blood pressure lowering effect of antihypertensive drugs, such as methyldopa and clonidine.
  • Increased risk of disruption of the body's ion balance, if taken with diuretic drugs.
  • Increased risk of poisoning, if taken with lithium.
  • Increased risk of arrhythmias, if taken with procainamide, quinidine, and amiodarone.

In addition to some of the drugs above, fluphenazine can also cause fatal side effects when used with alcohol.

Fluphenazine Side Effects and Dangers

Some side effects that may occur after using fluphenazine are:

  • Akathisia, namely feeling restless, unable to stay still and an uncontrollable urge to move.
  • Dystonia, which is uncontrolled muscle movement.
  • Dyskinesia and tardive dyskinesia.
  • Stiffness in muscles.
  • Tremors or shaking.
  • Dizzy.
  • Headache.
  • Loss of appetite.
  • Blurred vision.
  • Constipation.
  • Irregular heartbeat (arrhythmia).
  • Changes in the frequency and color of the urine becomes darker.
  • Jaundice.

Check with your doctor if you experience the above symptoms or have an allergic drug reaction, such as an itchy skin rash, swelling of the lips and eyes, and difficulty breathing, after taking fluphenazine.