Maprotiline is a medication to treat depression. This drug is also sometimes used to treat anxiety disorders. Maprotiline is available in tablet form and should only be taken with a doctor's prescription.
Maprotiline works by balancing natural chemicals in the brain that control mood. By taking this drug, symptoms of depression or anxiety disorders will subside and your mood will improve.
Maprotiline trademarks: Maprotiline HCl, Tilsan 25, Sandepril
What is Maprotiline
| group | Tricyclic antidepressants |
| Category | Prescription drugs |
| Benefit | Overcoming depression symptoms |
| Consumed by | Mature |
| Maprotiline for pregnant and lactating women | Category B: Animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women. Maprotiline can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Tablet |
Precautions Before Taking Maprotiline
Maprotiline should only be used under a doctor's prescription. There are several things that must be considered before using this drug, including:
- Do not take maprotiline if you are allergic to this drug.
- Do not consume alcoholic beverages while taking maprotiline.
- Do not drive or do activities that require alertness after taking maprotiline.
- Do not stop taking maprotiline carelessly without consulting your doctor first.
- Tell your doctor if you have recently had a heart attack or have ever had a blood clotting disorder, breathing problems, kidney problems, liver disease, hyperthyroidism, or an enlarged prostate.
- Tell your doctor if you have a history of glaucoma, mental disorders, seizures, or have ever attempted suicide.
- If you are planning to have dental work or surgery, tell your doctor that you are taking maprotiline.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Maprotiline may affect blood sugar levels. If you suffer from diabetes, check your blood sugar levels regularly to the doctor.
- Maprotiline may make you more sensitive to sunlight. Avoid direct sunlight and use sunscreen if you want to leave the house during the day.
- See a doctor immediately if you have an allergic reaction to the drug or an overdose after taking maprotiline.
Dosage and Instructions for Use Maprotiline
Maprotiline dosage for depression is:
Mature
- Initial dose: 75 mg per day, which can be given once a day or in divided doses, for 2 weeks
- Maintenance dose: 75–150 mg per day
- Maximum dose: 225 mg per day
seniors
- Initial dose: 25 mg per day
- The dose can be increased gradually until it reaches a dose of 50–70 mg per day, depending on the patient's response to the drug
How to Take Maprotiline Correctly
Follow the doctor's recommendations and read the instructions for use listed on the packaging before using maprotiline.
If you are advised to take maprotiline 1 time a day, take it at bedtime, so you don't feel sleepy during the day.
Try to take maprotiline at the same time every day, for maximum benefits.
If you forget to take maprotiline, it is recommended to take it as soon as you remember it, if the break with the next schedule is not too close. If it is close, ignore it and do not double the dose.
Store maprotiline at room temperature. Do not store it in a humid place or in direct sunlight.
Maprotiline Interactions with Other Drugs
The use of maprotiline together with other drugs can cause drug interactions, including:
- Increased risk of fatal side effects, such as high fever, tremors, or seizures, when used with MAOIs . drugs
- Increased risk of QT prolongation with pimozide, sotalolol, indapamide, epinephrine, or antiarrhythmic drugs, such as procainamide and quinidine
- Increased levels of serotonin in the body which can cause dangerous side effects when used with amitriptyline or phenelzine
- Increased effectiveness of barbiturate drugs
In addition, the use of maprotiline with food or alcoholic beverages can also increase the risk of disorders of the central nervous system.
Maprotiline Side Effects and Dangers
Some side effects that may appear after taking maprotiline are:
- Blurred vision
- dry mouth
- Nauseous
- Constipation
- Anxious or restless
- Insomnia
- Dizzy
- Drowsiness
- Weak
- Headache
- Tremor
Check with your doctor if the side effects above don't go away or get worse. See your doctor immediately if you have an allergic reaction to the drug or a more serious side effect, such as:
- Dizzy and want to faint
- Dazed or confused
- hallucination
- Unnatural behavior changes
- Panic attack
- Suicide Desire
- Arrhythmia
- Memory disorder
- Fever
- Sore throat
- Yellowing of the skin and eyes (jaundice)
