Never Feel Pain? Maybe You Have CIPA

Don't feel pain when you get hurt, scalded, pinched, or cut by a sharp object? Eits, don't be proud just yet! Don't worry, you're suffering congenital insensitivity to pain with anhidrosis or CIPA.

CIPA is a rare congenital disease. This condition occurs when a person is unable to feel hot or cold temperatures, does not sweat (anhidrosis), and does not feel pain when injured, bumped, or injured.

This is the Cause of CIPA

Normally, when the body is injured, the nerve endings send messages to the brain in the form of pain or pain. Next, the brain will give orders to these body parts to stay away from the cause of the injury and make movements to protect themselves or reduce pain.

For example, when your hand is exposed to a hot object, the nerve endings in the skin of the hand will send a message to the brain in the form of pain. After that, the brain will respond reflexively to pull the hand away from the object.

now, in people who have CIPA, there is a mutation in the NTRK1 gene that is responsible for sending this message. As a result, even if exposed to hot objects or injured, CIPA sufferers will not respond because they do not feel pain.

In addition, this genetic mutation will also cause CIPA sufferers to be unable to sweat, even though they feel hot after exercising or when the weather is hot. Of course this is dangerous, because sweating is one of the body's ways to balance the temperature.

Is CIPA Dangerous?

The inability to feel pain and feel temperature causes CIPA sufferers to suffer frequent injuries. For example, because they don't feel sick, people with CIPA don't realize that there is a sharp object in their shoes and will continue to walk until their feet bleed, or accidentally drink a drink that is too hot to cause a blister in their mouth.

In addition, injuries to the skin, bones, or diseases of internal organs are often diagnosed too late because there are no pain signals from the body to the brain, making recovery longer and more difficult. The condition is also sometimes only known after complications arise, such as a severe infection.

Anhidrosis or the inability to sweat is also a problem for people with CIPA. This condition causes the patient to be more at risk of experiencing an increase in body temperature (hyperpyrexia). In some cases, problems in the form of dental caries, intelligence disorders, and difficulties in controlling bowel and bladder control in CIPA patients were also found.

CIPA can only be confirmed by genetic testing, and until now, there is no treatment that can cure CIPA disease. The best treatment that can be done is to teach CIPA sufferers about ways to prevent injuries and encourage them to do regular health checks.

nowSo, not feeling pain when you get hit or hurt doesn't mean you have super powers, right? This could be a symptom of CIPA. Do an examination to the doctor so that the cause can be determined. If detected early, at least you can take precautions to avoid serious injury and illness.