MAOIs - Benefits, dosage, side effects

MAOI or monoamine oxidase iinhibitors is a group of drugs used to treat overcome depression. MAO drugs inhibitors workinghinder compound chemical in the brain that plays a role in regulating emotions and thinking ability somebody.

MAOI drugs will inhibit the performance of noradrenaline and serotonin compounds to prevent the onset of depressive symptoms. Although safe to use, MAOIs can cause various side effects, especially when taken with certain foods. Therefore, MAOI users should follow the doctor's instructions.

Warning Before Taking MAOIs:

  • Women who are planning a pregnancy, are pregnant, or are breastfeeding, should consult a doctor before taking MAOIs.
  • It is recommended not to drive a vehicle or operate heavy machinery while using MAOIs, as they may cause drowsiness.
  • Do not consume alcoholic beverages while on treatment with MAOIs.
  • Avoid eating foods that contain tyramine, such as processed soybeans, while taking MAOIs.
  • Do not stop treatment suddenly without consulting your doctor first.
  • Avoid taking other antidepressants, pain medications, cold and allergy medications, and herbal supplements while taking MAOIs.
  • If an allergic reaction or overdose occurs after using MAOI medicines, see a doctor immediately.

MAOIs are thought to increase suicidal ideation or behavior in children and adolescents. Therefore, MAOI drugs should not be taken by children. In addition, depression sufferers who use MAOIs should be monitored for their condition, especially in the early weeks of using MAOIs

If you have signs of suicidal ideation in a person with depression, call your doctor immediately.

To get a more detailed explanation of the side effects, warnings, or interactions of each type of MAOI drug, please see the A-Z Drugs page.

Type and MAOI Dosage

The following is the distribution of MAOI doses according to the types of drugs:

Isocarboxazid

  • Mature: 30 mg/day. The maximum dose is 60 mg/
  • seniors: 5-10 mg/day.

Phenelzine

  • Mature: 15 mg, 3 times a day. The dose can be increased after 2 weeks.

tranylcypromine

  • Mature: 10-20 mg, 2 times a day.

Selegiline

  • Mature: 10 mg/day, or 6 mg/day if given in form patches (koyo).

MAOI Side Effects

MAOI antidepressant drugs can also cause side effects in sufferers. Some of the side effects that can appear are:

  • dry mouth
  • Nauseous
  • Constipation
  • Insomnia
  • Headache
  • Dizzy
  • Head dizzy
  • A reaction occurs in the area of ​​​​the skin where the MAOI patch is attached