Ceftazidime is an antibiotic drug to treat bacterial infections. Some infectious diseases that can be treated with this drug are pneumonia, meningitis, bone and joint infections, peritonitis, and urinary tract infections.
Ceftazidime is a third-generation cephalosporin antibiotic that works by interfering with the formation of bacterial cell walls, causing the bacteria to die. Please note that this medicine cannot treat infections caused by viruses or fungi.
Ceftazidime trademark: Biozyme, Cefdim, Ceftamax, Ceftazidime, Ceftazidime Pentahydrate, Ceftum, Centracef, Cetazum, Dimfec, Extimon, Forta, Fortum, Pharodime, Quazidim, Thidim, Zavicefta, Zibac, Zidifec, Zitadim
What is Ceftazidime
| group | Prescription drugs |
| Category | Cephalosporin antibiotics |
| Benefit | Overcoming bacterial infections |
| Used by | Adults and children |
| Ceftazidime for pregnant and lactating women | Category B:Animal studies have not shown a risk to the fetus, but there are no controlled studies in pregnant women. Ceftazidime is absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first |
| Shape | Inject |
Precautions Before Using Ceftazidime
Ceftazidime should not be used carelessly. There are several things you should pay attention to before using ceftazidime, namely:
- Tell your doctor if you are allergic to ceftazidime or to other cephalosporin antibiotics, such as cefotaxime or ceftrixaxone. This medicine should not be given to patients with these conditions.
- Tell your doctor if you have or have had colitis, severe diarrhea, muscle disorders, seizures, epilepsy, diabetes, congestive heart failure, malnutrition, kidney disease, or encephalopathy
- Tell your doctor if during your treatment with ceftazidime you plan to get vaccinated with a live vaccine, such as the typhoid vaccine. This medicine may decrease the effectiveness of the vaccine.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- See your doctor right away if you experience an allergic drug reaction, overdose, or serious side effect after using ceftazidime.
Dosage and Instructions for Use of Ceftazidime
Ceftazidime injection will be given directly by a doctor or medical officer under the supervision of a doctor. Ceftazidime injection will be given through a vein (intravenous/IV), muscle (intramuscular/IM), or intravenously.
The following is the dose of ceftazidime based on the condition to be treated and the age of the patient:
Condition: Prevention of infection due to complications of prostate surgery
- Mature: 1 gram concurrently with anesthesia. Can be repeated after catheter removal.
- Elderly >80 years old: The maximum dose is 3 grams per day.
Condition: Lung infection
- Mature: 100–150 mg/kg, every 8 hours. The maximum dose is 9 grams per day.
- Elderly >80 years old: The maximum dose is 3 grams per day.
- Children weighing 40 kg: 150 mg/kg body weight per day, divided into 3 doses. The maximum dose is 6 grams per day.
Condition: Bone and joint infections, abdominal organ infections, or severe skin infections
- Mature: 1-2 grams, every 8 hours.
- Elderly > 80 years: The maximum dose is 3 grams per day.
- Children weighing 40 kg: 100–150 mg/kgBW per day, divided into 3 doses. The maximum dose is 6 grams per day.
Condition: Meningitis or nosocomial pneumonia
- Mature: 2 grams, every 8 hours.
- Elderly >80 years old: The maximum dose is 3 grams per day.
- Children weighing 40 kg: 150 mg/kg body weight per day, divided into 3 doses. The maximum dose is 6 grams per day.
Condition: Urinary tract infection
- Mature: 1-2 grams, every 8-12 hours.
- Elderly >80 years old: The maximum dose is 3 grams per day.
- Children weighing 40 kg: 100–150 mg/kg body weight per day, divided into 3 doses. The maximum dose is 6 grams per day.
How to Use Ceftazidime Correctly
Ceftazidime injection will be given directly by a doctor or medical officer under the supervision of a doctor. Ceftazidime injection can be given through a vein directly, muscle, or through an IV fluid.
Do not stop taking medication without consulting your doctor first. Follow your doctor's advice while on treatment with ceftazidime. Your doctor will ask you to have regular blood tests or kidney function tests.
Ceftazidime Interactions with Other Drugs
The following are some of the side effects that may occur if ceftazidime is used with other medicines:
- Increased risk of kidney damage if used with aminoglycoside drugs, such as gentamicin
- Decreased effectiveness of live vaccines, such as BCG vaccine or typhoid vaccine
- Increased effectiveness of anticoagulant drugs, such as warfarin
- Increased blood levels of ceftazidime when used with probenecid
- Decreased effectiveness of hormonal contraceptives, such as birth control pills
Ceftazidime Side Effects and Dangers
There are several side effects that can occur after using ceftazidime, including:
- Nauseous
- Throw up
- Diarrhea
- Stomach ache
- Swelling, redness, or pain at the injection site
In addition to these side effects, there are also side effects in the form of pain, swelling, or irritation at the injection site. Consult a doctor if these side effects do not improve immediately or get worse.
See your doctor right away if you have an allergic drug reaction or any of the following serious side effects:
- Severe stomach ache
- Severe diarrhea or bloody diarrhea
- Confusion, trouble remembering, or speech impediments
- Jaundice
- Trembling or difficulty controlling movement
- Fingers feel cold, discolored, or have changes in the skin
