Vasopressin - Benefits, dosage and side effects

Vasopressin or vasopressin is a drug used to treat diabetes insipidus. This medication will help reduce the frequency of urination and control thirst. In addition, this drug can also be used in the treatment of esophageal variceal bleeding.

Vasopressin works by reducing the amount of urine produced by the kidneys and helps constrict (vasoconstrict) blood vessels, thereby helping regulate the frequency and amount of urine that comes out.

This drug also has the effect of triggering bowel movements, so it can be used to help process X-rays of the digestive tract.

Vasopressin trademark: Farpressin

What is Vasopressin

groupPrescription drugs
BenefitTreating diabetes insipidus and bleeding from esophageal varices
Used byMature
Vasopressin for pregnant and lactating womenCategory C:Animal studies have shown adverse effects on the fetus, but there are no controlled studies in pregnant women.

Drugs should only be used if the expected benefit outweighs the risk to the fetus.

It is not known whether vasopressin is absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first.

ShapeInjectable liquid

Precautions Before Using Vasopressin

Vasopressin should not be used carelessly. Before using this drug, you need to pay attention to the following points:

  • Tell your doctor about any allergies you have. Vasopressin should not be used by patients who are allergic to this drug.
  • Tell your doctor if you have or are currently suffering from coronary heart disease, kidney disease, asthma, migraine, epilepsy, seizures, or edema.
  • Tell your doctor if you are taking certain medications, supplements, or herbal products.
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • See your doctor right away if you have an allergic reaction, serious side effects, or overdose after taking vasopressin.

Dosage and Rules for Use of Vasopressin

The doctor will give the dose and determine the length of treatment according to the patient's condition. Vasopressin is available only as an injection and can be injected into a vein (intravenous/IV), into a muscle (intramuscularly/IM), or under the skin (subcutaneously/SC).

The following is a distribution of vasopressin doses based on the condition to be treated:

  • Condition:Diabetes insipidus

    Dosage 5–20 units, administered SC/IM, 2–3 times daily.

  • .Condition: Esophageal variceal bleeding

    A dose of 20 units, dissolved in an infusion of 100 ml of 5% glucose for 15 minutes.

MethodUsing Vasopressin Correctly

Vasopressin will be injected by a doctor or medical officer under the supervision of a doctor. This medicine will be injected into a vein (intravenous/IV), into a muscle (intramuscular/IM), or under the skin (subcutaneous/SC).

During therapy with vasopressin, the doctor will determine the amount of fluid you should consume, to avoid excess or lack of fluids.

In addition, you will also regularly undergo an examination of the heart record or EKG to monitor heart function. Follow the doctor's advice while undergoing therapy with vasopressin.

Vasopressin Interactions with Other Drugs

The use of vasopressin with other drugs can cause drug interactions, including:

  • Increased effectiveness of vasopressin when used with carbamazepine, fludrocortisone, chlorpropamide, clofibrate, or tricyclic antidepressants
  • Decreased effectiveness of vasopressin when used with demeclocycline, noradrenaline, lithium, or heparin
  • Increased risk of heart rhythm disturbances, i.e. QT prolongation syndrome if used with dolasetron, clozapine, or amiodarone
  • Increased risk of fluid retention and low blood sodium levels when used with indomethacin or ibuprofen

Vasopressin Side Effects and Dangers

Some of the side effects that can occur after using vasopressin are:

  • Pale
  • Nausea or vomiting
  • Stomach cramps or bloating
  • Excessive sweating
  • Shaky
  • Headache

Check with your doctor if the side effects above don't go away or get worse. See your doctor right away if you have an allergic reaction to a drug or a more serious side effect, such as:

  • Shortness of breath, chest pain, slow or irregular heart rate
  • Extremely heavy dizziness or unusual tiredness
  • Numbness or tingling in the hands or feet
  • Hyponatremia which can be characterized by symptoms such as headache, confusion, vomiting, or loss of balance
  • Water intoxication can be characterized by symptoms such as severe throbbing headache, drowsiness, or feeling very weak
  • Fainting or seizure